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Spesolimab

Cat# : THA-0133

Product Datasheets COA :
Cat#:  THA-0133
Product Name:  Spesolimab
Description:  Spesolimab is an interleukin-36 receptor antagonist used to treat generalized pustular psoriasis flares in adults.
Sequences:  Not Available
Molecular Weight:  146000.0 Da (approximate)
Introduction:  Spesolimab is an interleukin-36 (IL-36) receptor antagonist. It is a humanized monoclonal immunoglobulin G1 antibody that was produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. The biosimilar of the drug, spesolimab-sbzo, was first approved by the FDA in September 2022 to treat generalized pustular psoriasis flares. Spesolimab works by inhibiting the inflammatory signaling pathway of IL-36, which is often overexpressed and aberrantly overactive in generalized pustular psoriasis. Spesolimab received recommendations from the EMA's Committee for Medicinal Products for Human Use (CHMP) to be granted marketing authorization in October 2022 and was finally approved in December 2022 for the treatment of flares in adult patients with generalized pustular psoriasis.
Purity:  >99% by SDS-Page and HPLC analysis
Formula:  C6480H9988N1736O2012S46
Appearance:  Liquid
For research use only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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  • Size: 100ug 500ug 1mg 5mg 10mg 100mg 500mg 1g
  • Conjugation: None R-PE APC Biotin FITC Alexa Flour Others
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