After dominating the medicine catalog for decades, small molecules are
gradually giving market shares to a second, fast-growing class of drugs
– therapeutic proteins. Although the former is currently the main
therapeutic agent by number, the impact of protein therapeutics is increasing
thanks to advances in recombinant DNA technology and improved understanding
of disease pathology. These recombinant therapeutic proteins are also known
as biotechnological therapeutics and used for multiple purposes, including
diagnosis, prophylaxis, disease management, and/or cure. Moreover, protein
therapeutics are known to represent one-third of the entities that are
launched as new medicines under biologics.
Nowadays, the importance of therapeutic proteins as an important class
of medicines cannot be ignored by patients or the health care industry.
Recently approved protein therapeutics attach a wide range of clinical
disorders, including cancers, autoimmunity/inflammation, exposure to infectious
agents, and genetic disorders, which are difficult to treat by conventional
Since 2011, the U.S. Food and Drug Administration has approved 62 recombinant
therapeutic proteins, of which, over half of the approved therapeutic proteins
were indicated for oncology (26%) and hematology (29%), whereas the remaining
45% had primary indications in cardiology/vascular disease (5%), dermatology
(3%), endocrinology (6%), immunology (6%), infectious diseases (3%), musculoskeletal
(8%), ophthalmology (3%), pulmonary/respiratory disease (3%), and others.
For instance, IL-1Ra is used to treat metabolic disorders or endocrine
dysfunctions like type 2 diabetes mellitus and hemophilia, interferon-alpha
is used for the treatment of hepatitis C and erythropoietin for chronic
anemia, botulinum toxin type A and B are used for multiple dystonia and
lepirudin for heparin-induced thrombocytopenia.
Creative BioMart is specialized in discovery and manufacturing of recombinant
proteins, providing quality products for research use and as industrial
raw materials. On this page, you may find therapeutic proteins related
to different diseases. You may further contact us for help if you have
any trouble in searching for protein products
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