Recombinant TGEV S1 Protein

Specification

• Cat#: THP-0577
• Product Name: Recombinant TGEV S1 Protein
• Description: Recombinant TGEV (strain Attenuated H) S1 Protein is generated using a Mammalian expression system. The target gene encoding Ile29-Tyr774 is expressed with a C-terminal 6His tag.
• Molecular Weight: 82.9 kDa
• Introduction: Transmissible gastroenteritis coronavirus (TGEV), an enteropathogenic coronavirus, causes severe diarrhea in pigs and high mortality in suckling piglets. The spike (S) glycoprotein contains two domains; S1 is responsible for enteric tropism, sialic acid recognition, and host receptor binding. While TGEV S1 is well-characterized, its intracellular role remains less understood. TGEV infection upregulates UBXN1 expression in IPEC-J2 cells. UBXN1 inhibition via siRNA reduces viral titers and S1 expression, whereas UBXN1 overexpression increases viral copy numbers.
• Purity: Purity exceeds 95% as assessed by reducing SDS-PAGE (QC verified).
• Storage: Upon reconstitution, store samples at -20°C or lower. The product remains stable for a minimum of 24 months under recommended storage conditions.
• Shipping Conditions: Transported using dry ice packs. Immediate storage at the specified temperature is required upon receipt.
• Formulation: Provided as a 0.2 μm filtered solution in PBS, pH 7.4.
• Size: 50μg/500μg/1g