Recombinant MPXV A35R Protein

Specification

• Cat#: THP-0523
• Product Name: Recombinant MPXV A35R Protein
• Description: Recombinant MPXV A35R Protein is expressed in a Mammalian system. The target gene encoding Val57-Thr181 is expressed with a C-terminal 6His tag.
• Molecular Weight: 14.6 kDa
• Introduction: Monkeypox is a zoonotic disease caused by the monkeypox virus (MPXV), an orthopoxvirus. The highly conserved A35R gene encodes a hydrophobic acidic protein with little homology outside poxviruses, suggesting a unique virulence mechanism. A35R may interfere with antigen processing, presentation, or apoptosis regulation in infected cells. Its function appears necessary for growth in specific cell types, such as macrophages. A35R localizes to viral DNA factories and has been identified as a constitutive transcriptional activator in yeast two-hybrid studies.
• Purity: Purity exceeds 95% as assessed by reducing SDS-PAGE (QC verified).
• Storage: Upon reconstitution, store samples at -20°C or lower. The product remains stable for a minimum of 24 months under recommended storage conditions.
• Shipping Conditions: Transported using dry ice packs. Immediate storage at the specified temperature is required upon receipt.
• Formulation: Provided as a 0.2 μm filtered solution containing 20mM PB, 150mM NaCl, 0.1M Arginine, 20% Glycerol, and 5% Trehalose, pH 7.4.
• Size: 50μg/500μg/1g