Recombinant Influenza B (B/Yamagata/16/1988) NA Protein

Specification

• Cat#: THP-0517
• Product Name: Recombinant Influenza B (B/Yamagata/16/1988) NA Protein
• Description: Recombinant Influenza B (B/Yamagata/16/1988) Neuraminidase is produced by a Mammalian expression system. The target gene encoding Leu32-Leu466 is expressed with an N-terminal 6His tag.
• Molecular Weight: 55.1 kDa
• Introduction: Influenza B viruses (IBV) circulate globally alongside Influenza A viruses (IAV), causing significant annual epidemics. Neuraminidase (NA), a critical target for therapeutics and vaccines, is the second most abundant surface glycoprotein after HA (5-10 fold less). NA forms a tetrameric membrane glycoprotein composed of four identical monomers with a catalytic head, stalk, transmembrane domain, and cytoplasmic tail. While HA mediates viral attachment and entry, NA cleaves sialic acids to release progeny virions from host cells and prevents viral aggregation, thereby facilitating viral spread.
• Purity: Purity exceeds 90% as assessed by reducing SDS-PAGE (QC verified).
• Storage: Upon reconstitution, store samples at -20°C or lower. The product remains stable for a minimum of 24 months under recommended storage conditions.
• Shipping Conditions: Transported using dry ice packs. Immediate storage at the specified temperature is required upon receipt.
• Formulation: Provided as a 0.2 μm filtered solution in PBS, pH 7.4.
• Size: 50μg/500μg/1g