Recombinant HSV-2 (strain HG52) Envelope Glycoprotein E

Specification

• Cat#: THP-0504
• Product Name: Recombinant HSV-2 (strain HG52) Envelope Glycoprotein E
• Description: Recombinant HSV-2 (strain HG52) Envelope Glycoprotein E is generated using a Mammalian expression system. The target gene encoding Ala21-Arg414 is expressed with a C-terminal 6His tag.
• Molecular Weight: 43.8 kDa
• Introduction: Anterograde axonal transport of Herpes simplex virus (HSV) is essential for spreading the virus from latent ganglia to epithelial tissues for replication. This transport process is initiated by the viral membrane proteins gE/gI and US9, which facilitate virion movement from the cytoplasm to proximal axon segments. The gE/gI complex is also significant for cell-to-cell spread in cultured neurons and epithelial cells forming extensive junctions, such as keratinocytes and HEC-1A cells.
• Purity: Purity exceeds 95% as assessed by reducing SDS-PAGE (QC verified).
• Storage: Upon reconstitution, store samples at -20°C or lower. The product remains stable for a minimum of 24 months under recommended storage conditions.
• Shipping Conditions: Transported using dry ice packs. Immediate storage at the specified temperature is required upon receipt.
• Formulation: Provided as a 0.2 μm filtered solution in PBS, pH 7.4.
• Size: 50μg/500μg/1g