Recombinant HSV-1 (strain 17) Envelope Glycoprotein C

Specification

• Cat#: THP-0500
• Product Name: Recombinant HSV-1 (strain 17) Envelope Glycoprotein C
• Description: Recombinant HSV-1 Envelope Glycoprotein C is generated using a Mammalian expression system. The target gene encoding Glu27-His457 is expressed with a C-terminal His tag.
• Molecular Weight: 47.2 kDa
• Introduction: Herpes simplex virus (HSV) anterograde transport in neuronal axons facilitates spread from latent ganglia to epithelial tissues. HSV membrane proteins gE/gI and US9 initiate this transport. Glycoprotein C (gC) functions in viral entry and immune evasion by binding complement component C3b. HSV-1 gC protects essential entry glycoproteins, such as gB, from neutralization. Additionally, gC serves as the primary ligand for binding cell surface heparan sulfate proteoglycans and is a target for CD4 T-lymphocyte cytotoxicity.
• Purity: Purity exceeds 95% as assessed by reducing SDS-PAGE (QC verified).
• Storage: Upon reconstitution, store samples at -20°C or lower. The product remains stable for a minimum of 24 months under recommended storage conditions.
• Shipping Conditions: Transported using dry ice packs. Immediate storage at the specified temperature is required upon receipt.
• Formulation: Provided as a 0.2 μm filtered solution in PBS, pH 7.4.
• Size: 50μg/500μg/1g