Recombinant HCoV-HKU1 S-trimer Protein

Specification

• Cat#: THP-0497
• Product Name: Recombinant HCoV-HKU1 S-trimer Protein
• Description: Recombinant HCoV-HKU1 S-trimer Protein is expressed in a Mammalian system. The target gene encoding Ala13-Asn1276 is expressed with a C-terminal 6His tag.
• Molecular Weight: 144.8 kDa
• Introduction: The coronavirus spike (S) glycoprotein is essential for viral attachment to host cells at the onset of infection. It serves as a major immunogen and a target for entry inhibitors. The S protein is a large type I transmembrane protein composed of S1 and S2 subunits. S1 contains the receptor-binding domain (RBD) for recognizing cell surface receptors, while S2 contains elements required for membrane fusion. The S protein plays a key role in eliciting neutralizing antibodies, T-cell responses, and protective immunity.
• Purity: Purity exceeds 95% as assessed by reducing SDS-PAGE (QC verified).
• Storage: Upon reconstitution, store samples at -20°C or lower. The product remains stable for a minimum of 24 months under recommended storage conditions.
• Shipping Conditions: Transported using dry ice packs. Immediate storage at the specified temperature is required upon receipt.
• Formulation: Provided as a 0.2 μm filtered solution in PBS, pH 7.4.
• Size: 50μg/500μg/1g