Recombinant HCoV-229E Nucleocapsid Protein

Specification

• Cat#: THP-0496
• Product Name: Recombinant HCoV-229E Nucleocapsid Protein
• Description: Recombinant HCoV-229E Nucleocapsid Protein is produced by an E. coli expression system. The target gene encoding Met1-Asn389 is expressed with an N-terminal 6His tag.
• Molecular Weight: 47.2 kDa
• Introduction: The Coronavirus Nucleocapsid (N) protein is essential for viral RNA synthesis and possesses RNA chaperone activity that may facilitate template switching. As the most abundant viral protein, N protein packages the positive-strand viral genome into a helical ribonucleocapsid (RNP). It plays a fundamental role in virion assembly through interactions with the viral genome and membrane protein M. Furthermore, it enhances the efficiency of subgenomic viral RNA transcription and viral replication. Due to its sequence conservation and strong immunogenicity, the coronavirus N protein is a preferred target for diagnostic applications.
• Purity: Purity exceeds 85% as assessed by reducing SDS-PAGE (QC verified).
• Storage: Upon reconstitution, store samples at -20°C or lower. The product remains stable for a minimum of 24 months under recommended storage conditions.
• Shipping Conditions: Transported using dry ice packs. Immediate storage at the specified temperature is required upon receipt.
• Formulation: Provided as a 0.2 μm filtered solution containing 50mM Tris-HCl, 150mM NaCl, and 50mM Arginine, pH 7.5.
• Size: 50μg/500μg/1g