Recombinant FCoV S Protein RBD

Specification

• Cat#: THP-0492
• Product Name: Recombinant FCoV S Protein RBD
• Description: Recombinant FCoV S Protein RBD is produced by a Mammalian expression system. The target gene encoding Asn256-Asp566 is expressed with a C-terminal 6His tag.
• Molecular Weight: 36.3 KDa
• Introduction: Feline coronavirus (FCoV), an enveloped positive-sense RNA virus, is a common pathogen in cats with two pathotypes: feline enteric coronavirus (FECV) and feline infectious peritonitis virus (FIPV). Infection relies on the interaction between the receptor-binding domain (RBD) of the spike (S) protein and host cell receptors. The S protein determines cell tropism, induces neutralizing antibodies, and regulates cell entry. It is considered the main driver of viral tropism and virulence changes. Historical serotype classification based on antigenic differences underscores the importance of the S protein in FCoV pathogenesis.
• Purity: Purity exceeds 95% as assessed by reducing SDS-PAGE (QC verified).
• Storage: Upon reconstitution, store samples at -20°C or lower. The product remains stable for a minimum of 24 months under recommended storage conditions.
• Shipping Conditions: Transported using dry ice packs. Immediate storage at the specified temperature is required upon receipt.
• Formulation: Provided as a 0.2 μm filtered solution in PBS, pH 7.4.
• Size: 50μg/500μg/1g