Recombinant CSFV E2 Protein

Specification

• Cat#: THP-0490
• Product Name: Recombinant CSFV E2 Protein
• Description: Recombinant CSFV (strain HC20WB01) E2 Protein is produced by a Mammalian expression system. The target gene encoding Arg690-Glu1030 is expressed with an N-terminal 6His tag.
• Molecular Weight: 39.1 kDa
• Introduction: Classical swine fever (CSF), caused by the classical swine fever virus (CSFV), is a highly contagious disease causing significant economic losses in pigs and wild boar. CSFV is an enveloped, single-stranded positive-sense RNA virus. Its 12.3 kb genome encodes a single polyprotein precursor processed into mature structural and nonstructural proteins. Structural proteins include the nucleocapsid protein C and envelope glycoproteins E0 (Erns), E1, and E2. Glycoproteins exist as disulfide-bonded homo- and heterodimers. E2 is the most immunogenic protein and the primary target for neutralizing antibodies. Erns, a homodimer found in virions and secreted from infected cells, serves as a secondary target for neutralizing antibodies.
• Purity: Purity exceeds 95% as assessed by reducing SDS-PAGE (QC verified).
• Storage: Upon reconstitution, store samples at -20°C or lower. The product remains stable for a minimum of 24 months under recommended storage conditions.
• Shipping Conditions: Transported using dry ice packs. Immediate storage at the specified temperature is required upon receipt.
• Formulation: Provided as a 0.2 μm filtered solution in PBS, containing 300mM NaCl, 20% Glycerol, and 0.02% Tween 80, pH 7.4.
• Size: 50μg/500μg/1g