Recombinant CAdV-1 (strain RI261) Fiber

Specification

• Cat#: THP-0489
• Product Name: Recombinant CAdV-1 (strain RI261) Fiber
• Description: Recombinant CAdV-1 (strain RI261) Fiber protein is expressed in an E. coli system. The target gene encoding Thr365-Gln543 is expressed with an N-terminal 6His tag.
• Molecular Weight: 21.1 KDa
• Introduction: Canine adenovirus (CAdV), a member of the Mastadenovirus genus, causes severe viral diseases in dogs globally. Two types exist: CAdV-1, causing infectious hepatitis and fox encephalitis, and CAdV-2, causing infectious laryngotracheitis and enteritis. CAdV-2 differs from CAdV-1 in virulence, antigen structure, and tissue tropism. CAdV-2 infection leads to high fever, cough, tonsillitis, pneumonia, vomiting, and diarrhea, and is a major cause of canine viral enteritis. The capsid contains three major proteins: Fiber, Hexon, and Penton. The Fiber protein is crucial for infection by attaching to specific cell surface receptors, while the Penton base facilitates virus internalization.
• Purity: Purity exceeds 95% as assessed by reducing SDS-PAGE (QC verified).
• Storage: Upon reconstitution, store samples at -20°C or lower. The product remains stable for a minimum of 24 months under recommended storage conditions.
• Shipping Conditions: Transported using dry ice packs. Immediate storage at the specified temperature is required upon receipt.
• Formulation: Provided as a 0.2 μm filtered solution in PBS, pH 7.4.
• Size: 50μg/500μg/1g