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Tenecteplase; Modified Tissue plasminogen activator (tPA)

Cat# : THP-0020

Product Datasheets COA :
Catalog# Product Name Availability Size Price Qty
THP-0020 Tenecteplase; Modified Tissue plasminogen activator (tPA) October 08, 2024 100ug $798.00
500ug $2,498.00
1mg $3,998.00
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Cat#:  THP-0020
Product Name:  Tenecteplase; Modified Tissue plasminogen activator (tPA)
Cas No:  191588-94-0
Description:  Tissue plasminogen activator (tPA). The product is a 527 amino acid glycoprotein developed by introducing the following modifications to the complementary DNA (cDNA) for natural human tPA: a substitution of threonine 103 with asparagine, and a substitution of asparagine 117 with glutamine, both within the kringle 1 domain, and a tetra-alanine substitution at amino acids 296-299 in the protease domain.
Sequences:  SYQVICRDEKTQMIYQQHQSWLRPVLRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGNWSTAESGAECTNWQSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCGLRQYSQPQFRIKGGLFADIASHPWQAAIFAAAAASPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMRP
Species:  Human
Molecular Weight:  58951.2 Da
Purity:  >99% by SDS-Page and HPLC analysis
Formula:  C2561H3919N747O781S40
Endotoxin:  <0.001 EU per 1 μg by the LAL method
Biological Activity:  8KU/vial
Application:  For treatment of myocardial infarction and lysis of intracoronary emboli.
For research use only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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  • Size: 100ug 500ug 1mg 5mg 10mg 100mg 500mg 1g
  • Conjugation: None R-PE APC Biotin FITC Alexa Flour Others
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