Cetuximab, Recombinant Anti-Human EGFR Monoclonal Antibody

Specification

• Cat#: THA-0007
• Product Name: Cetuximab, Recombinant Anti-Human EGFR Monoclonal Antibody
• Description: Cetuximab is a recombinant chimeric human/mouse IgG1 monoclonal antibody that competitively binds to epidermal growth factor receptor (EGFR) and competitively inhibits the binding of epidermal growth factor (EGF).
• Sequences: Not Available
• Species: Human
• Molecular Weight: The predicted MW is 49/23 kDa.
• Source: CHO
• Purity: > 99% as determined by SDS-PAGE and SEC-HPLC.
• Formula: Liquid in 1x PBS, pH 7.4, sterile filtered, no preservatives.
• Biological Activity: When antigen is immobilized at 2µg/mL (100 µL/well), the concentration for 50% of maximal effect (EC50) of this product is 0.03101 ug/ml.
• Storage: Store it under sterile conditions at -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 10.17mg/ml. Centrifuge the vial at 4°C before opening to recover the entire contents.
• Endotoxin Level: < 0.1 EU per mg protein as determined by the LAL method.