Tasonermin

Specification

• Cat#: THP-0175
• Product Name: Tasonermin
• Cas No: 94948-59-1
• Description: The product is recombinant soluble form tumor necrosis factor alpha(TNF alpha) expressed in E.coli.
• Sequences: VRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
• Molecular Weight: 17724.0 Da
• Source: E. coli
• Purity: >99% by SDS-Page and HPLC analysis
• Formula: Not Available
• Endotoxin: <0.001 EU per 1 μg of the peptide by the LAL method
• Application: For use in adults as an adjunct to surgery for subsequent removal of the tumour so as to prevent or delay amputation, or in palliative care, for irresectable soft tissue sarcoma of the limbs. Used in combination with melphalan via mild hyperthermic isolated limb perfusion.
• Concentration: 1mg/5ml

Pharmaceutical Information

• Pharmaceutical Application: Tasonermin
• Targets: Target 1. Tumor necrosis factor receptor superfamily member 1A; Target 2. Tumor necrosis factor receptor superfamily member 1B