rhIGFBP-3, Recombinant human insulin-like growth factor binding protein-3

Catalog#	Product Name	Availability	Size	Price	Qty
THP-0205	rhIGFBP-3, Recombinant human insulin-like growth factor binding protein-3	June 05, 2023	1 vial	$3,998.00
Add to Cart Online Order Request a Bulk Order

Specification Drug Information Related Products

Cat#:	THP-0205
Product Name:	rhIGFBP-3, Recombinant human insulin-like growth factor binding protein-3
Description:	Recombinant human insulin-like growth factor binding protein-3 is a member of the insulin-like growth factor binding protein (IGFBP) family. This family includes IGFBP-1 to IGFBP-6 that bind to the insulin-like growth factors (IGFs), thus regulating the half-life, activity, transport, and tissue distribution of the IGFs. Structurally, the IGFBP family of proteins is defined by highly homologous amino and carboxy terminal domains with a structurally diverse central region.
Sequences:	Not Available
Species:	Human
Molecular Weight:	Not Available
Purity:	>99% by SDS-Page and HPLC analysis
Cas No:	Not Available
Formula:	Not Available
Endotoxin Level:	<0.001 EU per 1 μg of the peptide by the LAL method

Drug Name:	rhIGFBP-3
Applications:	Investigated for use/treatment in cancer/tumors (unspecified).
Examples of Clinical Use:	Cancer/tumors (unspecified)
Pharmacodynamics:	Not Available
Mechanism of action:	rhIGFBP-3 is a protein that is normally found in our bloodstream that has been shown to induce cancer cell death in a variety of experimental systems. Several studies have demonstrated that cancer risk increases with decreasing levels of circulating IGFBP-3. IGFBP-3 can induce cell cycle arrest and enhance the efficacy of chemotherapeutic agents.
Affected organisms:	Not Available
Targets:	Target 1. Insulin-like growth factor 1 receptor