Aprotinin; Bovine pancreatic trypsin inhibitor (BPTI)

Specification

• Cat#: THP-0012
• Product Name: Aprotinin; Bovine pancreatic trypsin inhibitor (BPTI)
• Cas No: 9087-70-1
• Description: The bovine pancreatic trypsin inhibitor, BPTI is a protein with the main effect of slowing down of fibrinolysis.
• Sequences: RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCGGA
• Species: Bovine
• Molecular Weight: 6511.439 Da
• Formula: C284H432N84O79S7
• Endotoxin: <0.001 EU per 1 μg by the LAL method
• Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 °C for 1 week. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
• Application: For prophylactic use to reduce perioperative blood loss and the need for blood transfusion in patients undergoing cardiopulmonary bypass in the course of coronary artery bypass graft surgery who are at an increased risk for blood loss and blood transfusion.

Pharmaceutical Information

• Pharmaceutical Application: Aprotinin
• Targets: Target 1. Trypsin-1; Target 2. Chymotrypsinogen B; Target 3. Plasminogen; Target 4. Kallikrein-1