Polyferon Interferon gamma (IFN-g)

Specification

• Cat#: THP-0229
• Product Name: Polyferon Interferon gamma (IFN-g)
• Description: Interferon gamma (IFN-g) is produced by lymphocytes which have been activated by specific antigens or mitogens.
• Sequences: MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC
• Species: Human
• Molecular Weight: 15.6 kDa
• Source: E. coli
• Introduction: IFN-g, in addition to having antiviral activity, has important immune-regulatory functions, it is a potent activator of macrophages, and has anti-proliferative effects on transformed cells and it can potentiate the anti-viral and anti-tumor effects of type I interferons. IFN-g mouse recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 134 amino acids and having a molecular mass of 15.6 kDa. The IFN-gamma is purified by proprietary chromatographic techniques.
• Purity: >99% by SDS-Page and HPLC analysis
• Endotoxin: <0.001 EU per 1 μg of the peptide by the LAL method
• Biological Activity: The specific activity as determined in a viral resistance assay is < 0.1 ng/ml, corresponding to a specific activity of 1 x 10＾7 U/mg.
• Reconstitution: It is recommended to reconstitute the lyophilized IFN-g in sterile distilled water not less than 100 μg/ml which can then be further diluted to other aqueous solutions.
• Application: IFN-g, in addition to having antiviral activity, has important immune-regulatory functions, it is a potent activator of macrophages, and has anti-proliferative effects on transformed cells and it can potentiate the anti-viral and anti-tumor effects of type I interferons.

Pharmaceutical Information

• Pharmaceutical Application: Polyferon