Anti-Human TNFSF13 Antibody (APRIL Neutralizing mAb)

Specification

• Cat#: THP-472
• Product Name: Anti-Human TNFSF13 Antibody (APRIL Neutralizing mAb)
• Description: VIS649 is a humanized IgG2 monoclonal antibody which inhibits a proliferation-inducing ligand (APRIL). VIS649 suppresses pathogenic immunoglobulins (IgA and IgM), while preserving antibody responses to mRNA-based vaccines against SARS-COV-2. VIS649 reduces urinary protein-to-creatinine ratio (UPCR) and glomerular filtration rate (GFR). VIS649 is promising for the research of IgA nephropathy (IgAN).
• Molecular Weight: 146.36 kDa
• Source: CHO
• Purity: 99.82% by SEC-HPLC
• Endotoxin: < 1 EU/mg
• Storage: Store at -80 centigrade for 2 years. Aliquots should be stored at the same temperature after first use to avoid multiple freeze-thaws.
• Reconstitution: The product can be reconstituted/diluted with sterile PBS or saline.
• Application: ELISA, FACS, Functional assay
• Concentration: 6.247 mg/mL
• p H: 5
• Formulation: Supplied as a 0.22 μm filtered solution in 100 mM Pro-Ac, 20 mM Arg, pH 5.0