Peginterferon alfa-2a

Specification

• Cat#: THP-0022
• Product Name: Peginterferon alfa-2a
• Cas No: 198153-51-4
• Description: The product is a modified form of recombinant interferon and is derived from the alfa-2a moeity of recombinant human interferon and acts by binding to human type 1 interferon receptors.
• Sequences: CDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFGFPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNLQESLRSKE
• Species: Human
• Molecular Weight: 60000.0 Da
• Formula: Not Available
• Endotoxin: <0.001 EU per 1 μg by the LAL method
• Application: The product is indicated for the treatment of HCV in combination with other antiviral drugs in patients over 5 years of age with compensated liver disease. May be used as a monotherapy in patients with contraindications to or significant intolerance to other anti-viral therapies. The product is also indicated as a monotherapy for adult patients with HBeAg positive and HBeAg negative chronic hepatitis B infection who havecompensated liver disease and evidence of viral replication and liver inflammation.
• Concentration: 180ug/ml

Pharmaceutical Information

• Pharmaceutical Application: Peginterferon alfa-2a
• Targets: Target 1. Interferon alpha/beta receptor 2; Target 2. Interferon alpha/beta receptor 1; Enzyme 1. Cytochrome P450 1A2