Insulin Detemir

Specification

• Cat#: THP-0126
• Product Name: Insulin Detemir
• Cas No: 169148-63-4
• Description: The product is a long-acting human insulin analogue. It is produced using recombinant DNA technology in yeast cells. This insulin analogue has a 14-C fatty acid, myristic acid, bound to the lysine amino acid at position B29. The myristoyl side chain increases self-association and albumin binding.
• Sequences: >Protein sequence for A chain GIVEQCCTSICSLYQLENYCN >Protein sequence for B chain FVNQHLCGSHLVEALYLVCGERGFFYTPK
• Species: Human
• Molecular Weight: 5916.9 Da
• Source: Yeast
• Formula: C267H402N64O76S6
• Endotoxin: <0.1 EU per 1 μg of the protein by the LAL method
• Biological Activity: 100U/ml
• Application: For the treatment of type 1 or 2 diabetes mellitus. May be used in combination with oral anti-diabetic agents in type 2 diabetic patients who are not in adequate metabolic control with oral anti-diabetic agents alone.

Pharmaceutical Information

• Pharmaceutical Application: Insulin Detemir
• Targets: Target 1. Insulin receptor; Enzyme 1. Cytochrome P450 1A2; Enzyme 1. Serum albumin.