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IFN-Omega 1 (IFNW1)

Cat# : THP-0253

Product Datasheets COA :
Catalog# Product Name Availability Size Price Qty
THP-0253 IFN-Omega 1 (IFNW1) June 16, 2024 1 vial $3,998.00
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Cat#:  THP-0253
Product Name:  IFN-Omega 1 (IFNW1)
Description:  IFN-Omega 1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 172 amino acids and having a molecular mass of 19.9kDa. The IFN-Omega 1 is purified by proprietary chromatographic techniques.
Sequences:  MCDLPQNHGL LSRNTLVLLH QMRRISPFLC LKDRRDFRFP QEMVKGSQLQ KAHVMSVLHE MLQQIFSLFH TERSSAAWNM TLLDQLHTGL HQQLQHLETC LLQVVGEGES AGAISSPALT LRRYFQGIRV YLKEKKYSDC AWEVVRMEIM KSLFLSTNMQ ERLRSKDRDL GSS.
Species:  Human
Molecular Weight:  19.9kDa
Source:  E. coli
Introduction:  IFN-Omega 1 is a type I IFN, that can be induced by virus-infected leukocytes. Type I IFN family members, which include IFN-alpha, IFN-beta, and IFN-omega, signal through IFNAR-1/IFNAR-2 receptor complex, and wield antiviral and antiproliferative activities. IFNW1 exhibits about 75% sequence homology with IFN-a, and contains 2 conserved disulfide bonds, which are essential for full biological activity.
Purity:  >95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Formulation:  Sterile Filtered White lyophilized (freeze-dried) powder. Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.
Biological Activity:  The ED50 was determined by a cytotoxicity assay using Human TF-1 cells is < 0.01 ng/ml, corresponding to a specific activity of > 100,000,000 units/mg.
Reconstitution:  It is recommended to reconstitute the lyophilized IFNW1 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
For research use only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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