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Growth Hormone-Releasing Hormone (GHRH)

Cat# : THP-0280

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Catalog# Product Name Availability Size Price Qty
THP-0280 Growth Hormone-Releasing Hormone (GHRH) May 18, 2024 1 vial $3,998.00
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Cat#:  THP-0280
Product Name:  Growth Hormone-Releasing Hormone (GHRH)
Description:  Recombinant Human Growth Hormone-Releasing Hormone (GHRH) protein (Tyr32-Leu75) was expressed with the Fc region of human IgG1 at the N-terminus.
Species:  Human
Molecular Weight:  33.5 kDa.
Source:  HEK293 Cells
Introduction:  The role of hypothalamic growth hormone-releasing hormone (GHRH) in the release of growth hormone (GH) from the pituitary is well established. Extra-hypothalamic growth hormone-releasing hormone (GHRH) plays an important role in infertility. Growth hormone releasing hormone (GHRH) has recently been shown to increase the level of gamma-aminobutyric acid (GABA) and activate GABA receptors (GABARs) in the cerebral cortex. GABA is an inhibitory neurotransmitter that can inhibit seizures. GHRH may play an important role in inhibiting seizures by activating GABAARs. GHRH is produced by tumor cells, acts in an autocrine/paracrine manner, and requires the presence of GHRH receptor (GHRH-R) on the tumor cells to exert its effects. GHRH activity can be effectively blocked by synthetic antagonists of its receptor and hence, the expression of GHRH-R by tumor cells could serve as a predictor of response to GHRH-R antagonist therapy. The neurovascular protective effect of GHRH analogs during the early stage of diabetic retinopathy through their antioxidant and anti-inflammatory properties. GHRH antagonists can be a therapeutic option for thyroid cancer patients.
Purity:  > 85 % as determined by SDS-PAGE.
Formulation:  Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
For research use only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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  • Size: 100ug 500ug 1mg 5mg 10mg 100mg 500mg 1g
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