Cat# : THP-0038
| Catalog# | Product Name | Availability | Size | Price | Qty |
|---|---|---|---|---|---|
| THP-0038 | Dornase alfa; Human deoxyribunuclease I (DNase I) enzyme | October 31, 2025 | 500ug | $498.00 |
|
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| Cat#: | THP-0038 |
| Product Name: | Dornase alfa; Human deoxyribunuclease I (DNase I) enzyme |
| Cas No: | 143831-71-4 |
| Description: | The product is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is recombinantly produced in genetically modified CHO cells. The 260-amino acid sequence is identical to the endogenous human enzyme. The product cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products without affecting intracellular DNA. |
| Sequences: | LKIAAFNIQTFGETKMSNATLVSYIVQILSRYDIALVQEVRDSHLTAVGKLLDNLNQDAPDTYHYVVSEPLGRNSYKERYLFVYRPDQVSAVDSYYYDDGCEPCGNDTFNREPAIVRFFSRFTEVREFAIVPLHAAPGDAVAEIDALYDVYLDVQEKWGLEDVMLMGDFNAGCSYVRPSQWSSIRLWTSPTFQWLIPDSADTTATPTHCAYDRIVVAGMLLRGAVVPDSALPFNFQAAYGLSDQLAQAISDHYPVEVMLK |
| Species: | Human |
| Molecular Weight: | 29253.9 Da |
| Source: | CHO |
| Purity: | >99% by SDS-Page and HPLC analysis |
| Formula: | C1321H1999N339O396S9H |
| Endotoxin: | <0.001 EU per 1 μg of the peptide by the LAL method |
| Application: | Used as adjunct therapy in the treatment of cystic fibrosis. |
| Concentration: | 1 mg/1mL |
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