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Brain-Derived Neurotrophic Factor (BDNF)

Cat# : THP-0238

Product Datasheets COA :
Catalog# Product Name Availability Size Price Qty
THP-0238 Brain-Derived Neurotrophic Factor (BDNF) July 20, 2024 100ug $598.00
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Cat#:  THP-0238
Product Name:  Brain-Derived Neurotrophic Factor (BDNF)
Description:  Brain-derived Neurotrophic Factor Human Recombinant produced in E.Coli is a homodimer, non-glycosylated, polypeptide chain containing 2 x 119 amino acids (and an N-terminal Met) and having a total molecular mass of 27kDa.
Sequences:  MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR.
Species:  Human
Molecular Weight:  27 kDa
Source:  E. Coli
Introduction:  BDNF promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. BDNF is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the cns. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (ltp), long-term depression (ltd), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Purity:  >97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Formulation:  Sterile Filtered White lyophilized (freeze-dried) powder. The protein was lyophilized without any additives.
Biological Activity:  The ED50, as determined by the dose-dependent induction of C6 cells proliferation, is 1.3-2µg/ml.
Reconstitution:  It is recommended to reconstitute the lyophilized BDNF in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
For research use only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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  • Conjugation: None R-PE APC Biotin FITC Alexa Flour Others
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