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Angiopoietin-Like Protein 6 (ANGPTL6)

Cat# : THP-0278

Product Datasheets COA :
Catalog# Product Name Availability Size Price Qty
THP-0278 Angiopoietin-Like Protein 6 (ANGPTL6) October 07, 2024 1 vial $3,998.00
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Cat#:  THP-0278
Product Name:  Angiopoietin-Like Protein 6 (ANGPTL6)
Description:  ANGPTL6 Human Recombinant produced in E.coli is a polypeptide chain containing 460 amino acids and having a total molecular mass of 50.7 kDa. ANGPTL6 contains a N-Terminal 10 aa His-Tag.
Sequences:  MKHHHHHHAS RAGAPRCTYT FVLPPQKFTG AVCWSGPAST RATPEAANAS ELAALRMRVG RHEELLRELQ RLAAADGAVA GEVRALRKES RGLSARLGQL RAQLQHEAGP GAGPGADLGA EPAAALALLG ERVLNASAEA QRAAARFHQL DVKFRELAQL VTQQSSLIAR LERLCPGGAG GQQQVLPPPP LVPVVPVRLV GSTSDTSRML DPAPEPQRDQ TQRQQEPMAS PMPAGHPAVP TKPVGPWQDC AEARQAGHEQ SGVYELRVGR HVVSVWCEQQ LEGGGWTVIQ RRQDGSVNFF TTWQHYKAGF GRPDGEYWLG LEPVYQLTSR GDHELLVLLE DWGGRGARAH YDGFSLEPES DHYRLRLGQY HGDAGDSLSW HNDKPFSTVD RDRDSYSGNC ALYQRGGWWY HACAHSNLNG VWHHGGHYRS RYQDGVYWAE FRGGAYSLRK AAMLIRPLKL
Species:  Human
Molecular Weight:  50.7 kDa
Source:  E. coli
Introduction:  ANGPTL6 was originally named angiopoietin-related growth factor (AGF) having an N-terminal coiled-coil-like domain and a C-terminal fibrinogen-like domain, both of which are conserved in ANG. It is a circulating protein secreted by liver that induces angiogenesis by direct effect of epidermal ANGPTL6 on endothelial cells and proliferation of skin cells, and thereby promotes wound healing. It was concluded that ANGPTL6 is a hepatocyte-derived circulating factor that counteracts obesity and obesity-related insulin resistance, meaning that ANGPTL6 may be a novel biomarker for metabolic diseases. ANGPTL6 is a protein-coding gene which takes part is several processes. ANGPTL6 is involved in the wound healing process, promotes the chemotactic activity of endothelial cells and induce neovascularization. ANGPTL6 also counteracts high-fat diet-induced obesity and related insulin resistance through increased energy expenditure. Additionally ANGPTL6 promotes epidermal proliferation, remodeling and regeneration. Diseases linked with ANGPTL6 include enterobiasis, and gnathomiasis.
Purity:  >90.0% as determined by SDS-PAGE.
Formula:  White lyophilized (freeze-dried) powder. Filtered (0.4 µm) and lyophilized from a 0.5mg/ml solution containing 0.05M Acetate buffer pH 4.0.
Application:  ANGPTL6 is involved in the wound healing process, promotes the chemotactic activity of endothelial cells and induce neovascularization. ANGPTL6 also counteracts high-fat diet-induced obesity and related insulin resistance through increased energy expenditure. Additionally ANGPTL6 promotes epidermal proliferation, remodeling and regeneration.
For research use only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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  • Size: 100ug 500ug 1mg 5mg 10mg 100mg 500mg 1g
  • Conjugation: None R-PE APC Biotin FITC Alexa Flour Others
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