Cat# : THP-0007
Catalog# | Product Name | Availability | Size | Price | Qty |
---|---|---|---|---|---|
THP-0007 | Aldesleukin; Recombinant Modified Human interleukin-2 | October 08, 2024 | 100ug | $798.00 |
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Cat#: | THP-0007 |
Product Name: | Aldesleukin; Recombinant Modified Human interleukin-2 |
Cas No: | 110942-02-4 |
Description: | The product, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from native interleukin-2 in the following ways: a) The product is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon for this amino acid was deleted during the genetic engineering procedure; c) the molecule has serine substituted for cysteine at amino acid position 125. |
Sequences: | MAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT |
Species: | Human |
Molecular Weight: | 15314.8 Da |
Source: | E. coli |
Purity: | >99% by SDS-Page and HPLC analysis |
Formula: | C690H1115N177O202S6 |
Endotoxin: | <0.001 EU per 1 μg of the peptide by the LAL method |
Biological Activity: | 22000000 unit / vial |
Storage: | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 °C for 1 week. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Application: | For treatment of adults with metastatic renal cell carcinoma. |
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