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Aldesleukin; Recombinant Modified Human interleukin-2

Cat# : THP-0007

Product Datasheets COA :
Catalog# Product Name Availability Size Price Qty
THP-0007 Aldesleukin; Recombinant Modified Human interleukin-2 October 08, 2024 100ug $798.00
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Cat#:  THP-0007
Product Name:  Aldesleukin; Recombinant Modified Human interleukin-2
Cas No:  110942-02-4
Description:  The product, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from native interleukin-2 in the following ways: a) The product is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon for this amino acid was deleted during the genetic engineering procedure; c) the molecule has serine substituted for cysteine at amino acid position 125.
Sequences:  MAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
Species:  Human
Molecular Weight:  15314.8 Da
Source:  E. coli
Purity:  >99% by SDS-Page and HPLC analysis
Formula:  C690H1115N177O202S6
Endotoxin:  <0.001 EU per 1 μg of the peptide by the LAL method
Biological Activity:  22000000 unit / vial
Storage:  Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 °C for 1 week. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Application:  For treatment of adults with metastatic renal cell carcinoma.
For research use only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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  • Size: 100ug 500ug 1mg 5mg 10mg 100mg 500mg 1g
  • Conjugation: None R-PE APC Biotin FITC Alexa Flour Others
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