Tirzepatide

Specification

• Cat#: THP-0350
• Product Name: Tirzepatide
• Cas No: 2023788-19-2
• Description: Tirzepatide is a dual GIP and GLP-1 receptor agonist used for the treatment of type II diabetes in adults as an adjunct to diet and exercise.
• Sequences: >Tirzepatide protein sequence
  YXEGTFTSDYSIXLDKIAQKAFVQWLIAGGPSSGAPPPS
• Species: Human
• Molecular Weight: 4810.52 Da
• Introduction: Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Dual GIP/GLP-1 agonists gained increasing attention as new therapeutic agents for glycemic and weight control as they demonstrated better glucose control and weight loss compared to selective GLP-1 receptor agonists in preclinical and clinical trials. Tirzepatide comprises a 39 amino acid linear synthetic peptide conjugated to a C20 fatty diacid moiety. Its protein sequence was based on the sequence of endogenous GIP, and its pharmacological action on GLP-1 receptors is comparable to endogenous GIP; however, the long half-life of tirzepatide allows for once-weekly dosing.
• Formula: C225H348N48O68
• Biologic Classification: Protein Based Therapies
  Peptides
• Physical Appearance: Solid