Recombinant Human Antithrombin(rhAT)/Antithrombin Alfa

Specification

• Cat#: THP-0053
• Product Name: Recombinant Human Antithrombin(rhAT)/Antithrombin Alfa
• Cas No: 84720-88-7
• Description: Recombinant Human Antithrombin
• Sequences: HGSPVDICTA KPRDIPMNPM CIYRSPEKKA TEDEGSEQKI PEATNRRVWE LSKANSRFAT TFYQHLADSK NDNDNIFLSP LSISTAFAMT KLGACNDTLQ QLMEVFKFDT ISEKTSDQIH FFFAKLNCRL YRKANKSSKL VSANRLFGDK SLTFNETYQD ISELVYGAKL QPLDFKENAE QSRAAINKWV SNKTEGRITD VIPSEAINEL TVLVLVNTIY FKGLWKSKFS PENTRKELFY KADGESCSAS MMYQEGKFRY RRVAEGTQVL ELPFKGDDIT MVLILPKPEK SLAKVEKELT PEVLQEWLDE LEEMMLVVHM PRFRIEDGFS LKEQLQDMGL VDLFSPEKSK LPGIVAEGRD DLYVSDAFHK AFLEVNEEGS EAAASTAVVI AGRSLNPNRV TFKANRPFLV FIREVPLNTI IFMGRVANPC VK (Disulfide bridge: 8-128, 21-95, 247-430; Glycosylation site: 95, 135, 155, 192)
• Species: Human
• Molecular Weight: 49032.5271 Da
• Purity: >99% by SDS-Page and HPLC analysis
• Formula: C2191H3451N583O656S18
• Endotoxin: <0.001 EU per 1 μg by the LAL method
• Biological Activity: 1750U/ml
• Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 °C for 1 week. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
• Application: The product is a recombinant antithrombin it is indicated for the prevention of peri-operative and peri-partum thromboembolic events in patients with hereditary deficiency of antithrombin.

Pharmaceutical Information

• Pharmaceutical Application: Antithrombin Alfa
• Targets: Target 1. Prothrombin; Target 2. Coagulation factor X