Recombinant HSV-8 ORF65 and ORF8 Antigen, GST-tagged

Specification

• Cat#: HER-335
• Product Name: Recombinant HSV-8 ORF65 and ORF8 Antigen, GST-tagged
• Description: The E. coli derived recombinant protein contains the C-terminal immunodominant regions from ORF65 140-170 a.a. and N-terminal regions from ORF8 32-62 a.a. The protein is fused with a GST tag.
• Species: HSV-8
• Introduction: Entry of HSV into the host cell involves interactions of several viral glycoproteins with cell surface receptors. The virus particle is covered by an envelope which, when bound to specific receptors on the cell surface, will fuse with the cell membrane and create an opening, or pore, through which the virus enters the host cell. The sequential stages of HSV entry are analagous to those of other viruses. At first, complementary receptors on the virus and cell surface bring the two membranes into proximity. In an intermediate state, the two membranes begin to merge, forming a hemifusion state. Finally, a stable entry pore is formed through which the viral envelope contents are introduced to the host cell.
• Purity: HSV-8 Mosaic protein is >95% pure as determined by 10% PAGE (coomassie staining).
• Formulation: 100mM NaCl, 0.1% SDS and 50% glycerol.
• Stability: HSV-8 Mosaic protein although stable at 4°C for 1 week, should be stored below -18°C.Please prevent freeze thaw cycles.
• Physical Appearance: Sterile Filtered clear solution.
• Usage: All the products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Pharmaceutical Information

• Applications: HSV-8 Mosaic antigen is suitable for ELISA and Western blots, excellent antigen for detection of HSV with minimal specificity problems.