Recombinant Dengue Virus Subtype 2 produced in insect cells is a polypeptide chain containing amino acids 281-675 and having a molecular weight of approximately 50 kDa.Dengue Envelope-2 is purified by proprietary chromatographic technique.
Caused by one of four closely related virus serotypes of the genus Flavivirus, family Flaviviridae, each serotype is sufficiently different that there is no cross-protection and epidemics caused by multiple serotypes (hyperendemicity) can occur. In cell culture experiments and mice Morpholino antisense oligos have shown specific activity against Dengue virus.
Protein is >95% pure as determined by 12.5% SDS-PAGE.
Dengue Envelope-2 protein solution in 1xD-PBS, pH7.4, 0.1% Thimerosal, 5mM EDTA, 1µg/ml of Leupeptin, Aprotinin and Pepstatin A.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
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without prior written approval from Creative BioMart.
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