Recombinant CoV-2-S1 Protein, Fc-tagged

Specification

• Cat#: COV2-388
• Product Name: Recombinant CoV-2-S1 Protein, Fc-tagged
• Description: The HEK293 derived recombinant protein contains the Coronavirus 2019 Spike Glycoprotein S1 Receptor Binding Domain [RBD], Wuhan-Hu-1 strain, amino acids 319-541 fused to Fc tag at C-terminal.
• Species: CoV-2
• Source: HEK293 Cells.
• Introduction: A human infecting coronavirus (viral pneumonia) called 2019 novel coronavirus, 2019-nCoV was found in the fish market at the city of Wuhan, Hubei province of China on December 2019.The 2019-nCoV shares an 87% identity to the 2 bat-derived severe acute respiratory syndrome 2018 SARS-CoV-2 located in Zhoushan of eastern China. 2019-nCoV has an analogous receptor-BD-structure to that of 2018 SARS-CoV, even though there is a.a. diversity so thus the 2019-nCoV might bind to ACE2 receptor protein (angiotensin-converting enzyme 2) in humans.While bats are possibly the host of 2019-nCoV, researchers suspect that animal from the ocean sold at the seafood market was an intermediate host. RSCU analysis proposes that the 2019-nCoV is a recombinant within the viral spike glycoprotein between the bat coronavirus and an unknown coronavirus.
• Purity: Protein is >95% pure as determined SDS-PAGE.
• Formulation: CoV-S1 RBD proteinis lyophilized from 1x PBS pH-7.4 + 5% trehalose.
• Stability: Lyophilized Cov-2 S1 Glycoprotein RBD although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CoV2 Spike protein should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
• Physical Appearance: Lyophilized freezed dried powder.