Native Porcine Stomach Mucosa Pepsin

Specification

• Cat#: THP-171
• Product Name: Native Porcine Stomach Mucosa Pepsin
• Description: Pepsin is the principal proteolytic enzyme which occurs in the gastric juices of all mammals. Pepsinogen, its precursor, is secreted by the stomach mucosa. Activation of pepsinogen to pepsin is facilitated by the hydrogen ion concentration of the gastric juice, and it is accomplished autocatalytically by pepsin.Pepsin is an endopeptidase, which preferentially hydrolyzes those peptide linkages which involve the amino group contributed by the aromatic amino acids phenylalanine, tyrosine and tryptophan. Although pepsin digests proteins mainly into polypeptides of varying length, some shorter peptides and even some free amino acids, notably tyrosine and phenylalanine, may be released. The optimum pH for pepsin activity varies from 1.5-2.0 depending on the substrate. Pepsin from porcine stomach mucosa has been studied most extensively and has a molecular weight of 35,000.
• Species: Porcine Stomach Mucosa
• Molecular Weight: Pepsin from porcine stomach mucosa has been studied most extensively and has a molecular weight of 35,000.
• Source: Porcine Stomach Mucosa
• Stability: -20° C; -4° F
• Physical Appearance: Freeze-dried
• Optimal pH: PH 1.5-2.0