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Native Human Spleen Cathepsins D

Cat# : THP-126

Product Datasheets COA :
Cat#:  THP-126
Product Name:  Native Human Spleen Cathepsins D
Description:  Cathepsins are a group of intracellular proteolytic enzymes located within the lysosomes. On the basis of the specificity towards their substrates, the cathepsins have been assigned the names: Cathepsins A, B, C, D, E, G and L.Cathepsin D (EC 3.4.23.5) has been found to be widely distributed in various tissues but spleen is a rich source of this enzyme. Cathepsins A and D work synergistically to hydrolyze protein substrates. The rabbit liver Cathepsin D has a molecular weight of approximately 58,000 and it can be stored at 4° at pH 3-4 or at pH 8 for days without loss of significant amount of its activity (Press, E.M., Porter, R.R. and J. Cebra, Biochem J., 74, 501, 1960). Cathepsin D acts as a true proteinase on substrates such as denatured hemoglobin at the pH range of 2.8-3.0. In this respect it behaves enzymatically similar to pepsin.
Species:  Human Spleen
Molecular Weight:  The rabbit liver Cathepsin D has a molecular weight of approximately 58,000 .
Source:  Human Spleen
Stability:  Store at -20° C (-4° F)
Physical Appearance:  Freeze-dried powder
Not For Human Consumption!

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  • Size: 100ug 500ug 1mg 5mg 10mg 100mg 500mg 1g
  • Conjugation: None R-PE APC Biotin FITC Alexa Flour Others
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