Native Hexokinase

Specification

• Cat#: THP-146
• Product Name: Native Hexokinase
• Description: Hexokinase (HK) catalyzes the phosphorylation of glucose. In mammals, four distinct enzymes-types I to IV hexokinases-have been identified. The enzyme is found in most cells, but there is tissue specificity for the particular type of hexokinase. Thus skeletal muscle has type II, adipose tissue has both types I and II, and the liver has all four types of hexokinases. However, the type IV hexokinase (glucokinase) is the one that predominates in the liver (Human Biochemistry; Orten, J.M. and Neuhaus, O.W.; 10th edition, p. 226, 1982, Mosby, St. Louis).
• Molecular Weight: The yeast hexokinase has a molecular weight of 100,000 .
• Optimal pH: PH 7.5