Native Angiostatin

Specification

• Cat#: THP-0247
• Product Name: Native Angiostatin
• Description: Angiostatin is an internal proteolytic fragment of plasminogen, containing at least three Kringle domains.
• Species: Human
• Source: Native
• Introduction: The Kringle domains have specific anti-migratory and anti-proliferative activities. Angiostatin, an endogenous angiogenesis inhibitor, inhibits endothelial cell proliferation in vitro and angiogenesis in vivo. It is a potent and specific natural inhibitor of angiogenisis and metastatic tumor growth.
• Purity: >95 % SDS-PAGE.
• Formulation: Liquid
• Reconstitution: Constituents: 0.476% HEPES, 0.87% Sodium chloride.

Pharmaceutical Information

• Applications: Angiostatin, an endogenous angiogenesis inhibitor, inhibits endothelial cell proliferation in vitro and angiogenesis in vivo. It is a potent and specific natural inhibitor of angiogenisis and metastatic tumor growth.
• Examples of Clinical Use: Natural inhibitor of angiogenisis and metastatic tumor growth.
• Affected organisms: Humans