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Interleukin 7 (IL-7)

Cat# : THP-0268

Product Datasheets COA :
Catalog# Product Name Availability Size Price Qty
THP-0268 Interleukin 7 (IL-7) March 01, 2024 100ug $1,000.00
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Cat#:  THP-0268
Product Name:  Interleukin 7 (IL-7)
Description:  Interleukin 7 (IL-7) protein is produced by E. coli expression system.
Sequences:  MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH
Species:  Human
Molecular Weight:  17 kDa
Source:  E. coli
Introduction:  IL7, also known as interleukin 7, is a hematopoietic growth factor which belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRß) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes.
Purity:  > 95 % SDS-PAGE. This protein is purified by proprietary chromatographic techniques. Purity is greater than 98.0% as determined by RP-HPLC and SDS-PAGE.
Formulation:  Lyophilised
Biological Activity:  Biological Activity: The ED50 as determined by the dose-dependant stimulation of murine IXN/2B cells is <0.5ng/ml, corresponding to a Specific Activity of 2 x 106 IU/mg.
Reconstitution:  Reconstitute in sterile 18MOhm-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
For research use only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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