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Human Protein C

Cat# : THP-0017

Product Datasheets COA :
Catalog# Product Name Availability Size Price Qty
THP-0017 Human Protein C May 18, 2024 1 vial $3,998.00
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Cat#:  THP-0017
Product Name:  Human Protein C
Description:  The product is an endogenously occurring plasma protein that plays a key role within the coagulation cascade. Also known as blood coagulation factor XIV. The product is a zymogen, or enzyme precursor, of a vitamin K-dependent anticoagulant glycoprotein (serine protease) that is synthesized in the liver. It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface to Activated Protein C (APC). Once in its activated form, APC functions as a serine protease with potent anticoagulant effects, especially in the presence of its cofactor protein S. APC exerts its effect by inactivating essential components of the coagulation cascade (specifically factors V and VIII), which leads to a decrease in thrombin formation, and therefore a reduction in clot formation. The product pathway provides a natural mechanism for control of the coagulation system and prevention of excessive procoagulant responses to activating stimuli. A lack of blood coagulation factor XIV in the body would lead to unchecked coagulation activation, resulting in thrombin generation and intravascular clot formation with thrombosis. The product is available in concentrated form as the product Ceptrotin, which is indicated foruse in pediatric and adult patients with severe congenital deficiency for the prevention and treatment of venous thrombosis and purpura fulminans.
Sequences:  Not Available
Species:  Human
Molecular Weight:  Not Available
Cas No:  Not Available
Formula:  Not Available
Endotoxin Level:  <0.001 EU per 1 μg by the LAL method
Biological Activity:  100IU/ml
For research use only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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  • Size: 100ug 500ug 1mg 5mg 10mg 100mg 500mg 1g
  • Conjugation: None R-PE APC Biotin FITC Alexa Flour Others

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