The product is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype E.
<0.001 EU per 1 μg of the peptide by the LAL method
Equine Botulinum Neurotoxin E Immune FAB2
The product is indicted for use in documented or suspected exposure to botulinum toxin serotype E in adults and pediatric patients.
Examples of Clinical Use:
The product binds to botulinum toxin serotype E to prevent toxicity.
Mechanism of action:
Equine Botulinum Neurotoxin E Immune FAB2 is a mix of polyclonal antibodies for botulinum toxin type E. It binds to the toxin with high-affinity and prevents binding to ganglioside anchorage sites and membrane-bound receptors on cholinergic nerve terminals. This prevents internalization of the toxin into the cell and ultimately prevents it from exerting its toxic effects. Due to the long-lasting effects of botulinum toxin, the antibodies must be administered before symptoms present to prevent toxicity.
For research use only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products
without prior written approval from Creative BioMart.
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