Denenicokin, a recombinant peptide similar to or identical to endogenous human cytokine interleukin-21 (IL-21) with potential antineoplastic activity, binds to and activates IL-21 receptors, expressed on T-cells, B-cells, dendritic cells (DC), and natural killer (NK) cells, modulating the proliferation and/or differentiation of T and B cells, promoting T cell survival, and increasing the cytolytic activity of cytotoxic T lymphocytes (CTLs) and NK cells.
>99% by SDS-Page and HPLC analysis
<0.1 EU per 1 μg of the peptide by the LAL method
Metastatic or Recurrent Melanoma
Examples of Clinical Use:
Neoplasms by Site; Renal Cell Adenocarcinoma; Malignancies / Ovarian Cancer
For research use only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products
without prior written approval from Creative BioMart.
For more information on how our products could help advance your project, please contact us.