Cyanovirin-N (CV-N)

Specification

• Cat#: THP-0258
• Product Name: Cyanovirin-N (CV-N)
• Description: Cyanovirin-N (CV-N) (1-101aa) is expressed in E Coli or Yeast or Baculovirus or Mammalian Cell. This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
• Sequences: LGKFSQTCYN SAIQGSVLTS TCERTNGGYN TSSIDLNSVI ENVDGSLKWQ PSNFIETCRN TQLAGSSELA AECKTRAQQF VSTKINLDDH IANIDGTLKY E
• Species: Nostoc ellipsosporum
• Molecular Weight: 11,013 Da
• Source: E Coli or Yeast or Baculovirus or Mammalian Cell
• Introduction: Cyanovirin-N (CV-N) is a protein produced by the cyanobacterium Nostoc ellipsosporum that displays virucidal activity against several viruses, including human immunodeficiency virus (HIV). The virucidal activity of CV-N is mediated through specific high-affinity interactions with the viral surface envelope glycoproteins gp120 and gp41, as well as to high-mannose oligosaccharides found on the HIV envelope. In addition, CV-N is active against rhinoviruses, human parainfluenza virus, respiratory syncytial virus, and enteric viruses. The virucidal activity of CV-N against influenza virus is directed towards viral haemagglutinin. CV-N has a complex fold composed of a duplication of a tandem repeat of two homologous motifs comprising three-stranded beta-sheet and beta-hairpins.
• Purity: >=90% (lot specific)
• Application: CV-N is active against human immunodeficiency virus (HIV), rhinoviruses, human parainfluenza virus, respiratory syncytial virus, and enteric viruses.