Coral snake (micrurus fulvius) immune globulin antivenin (equine)

Specification

• Cat#: THP-0158
• Product Name: Coral snake (micrurus fulvius) immune globulin antivenin (equine)
• Description: The product is a horse-derived antiveninand is a refined, concentrated, and lyophilized preparation of serum globulins obtained by fractionating blood from healthy horses that have been immunized with eastern coral snake (Micrurus fulvius fulvius) venom.
• Sequences: Not Available
• Species: Horse
• Molecular Weight: Not Available
• Cas No: Not Available
• Formula: Not Available
• Endotoxin Level: <0.001 EU per 1 μg of the peptide by the LAL method
• Biological Activity: 250U/10ml

Pharmaceutical Information

• Pharmaceutical Application: Coral snake (micrurus fulvius) immune globulin antivenin (equine)
• Applications: This particular antivenin is indicated only for the treatment of envenomation caused by bites from Eastern coral snakes (Micrurus fulvius fulvius) and Texas coral snakes (Micrurus fulvius tenere). The agent will not neutralize the venom of Arizona (Sonoran) coral snakes (Micruroides euryxanthus) or that of South American species.
• Examples of Clinical Use: Snake venom of Eastern coral snakes and Texas coral snakes
• Pharmacodynamics: The product is standardized for potency in mice in terms of its LD50 neutralizing capacity per milliliter as determined by intravenous injection of a graded series of mixtures of thr product with M. f. fulvius venom. Based on this assay system, the reconstituted contents of each vial (10 mL) will neutralize about 250 mouse LD50 or approximately 2 mg of M. f. fulvius venom.
• Mechanism of action: North American Coral Snake Antivenin (Equine) is a preparation of serum globulins obtained by fractionating blood from healthy horses that have been immunized with eastern coral snake (Micrurus fulvius fulvius) venom.
• Affected organisms: Humans and other mammals