Coagulation Factor IX Human/F9

Specification

• Cat#: THP-0058
• Product Name: Coagulation Factor IX Human/F9
• Cas No: 9001-28-9
• Description: Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.
• Sequences: YNSGKLEEFVQGNLERECMEEKCSFEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGRCEQFCKNSADNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSVSQTSKLTRAEAVFPDVDYVNSTEAETILDNITQSTQSFNDFTRVVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT
• Species: Human
• Molecular Weight: 46548.2 Da
• Formula: C2041H3136N558O641S25
• Endotoxin: <0.001 EU per 1 μg of the protein by the LAL method
• Biological Activity: 3000IU
• Application: Factor IX is used to treat Christmas disease. Factor IX deficiency is treated by injection factor IX produced from human plasma. Tranexamic acid may be of value in patients undergoing surgery who have inherited factor IX deficiency in order to reduce the perioperative risk of bleeding.

Pharmaceutical Information

• Pharmaceutical Application: Coagulation Factor IX Human
• Targets: Target 1. Coagulation factor X; Target 2. Coagulation factor XI; Target 3. Coagulation factor VII; Target 4. Coagulation factor VIII; Target 5. Prothrombin; Target 6. Prolow-density lipoprotein receptor-related protein 1; Target 7. Vitamin K-dependent gamma-carboxylase