Calcium Voltage-Gated Channel Subunit Alpha1 S (CACNA1S)

Specification

• Cat#: THP-0262
• Product Name: Calcium Voltage-Gated Channel Subunit Alpha1 S (CACNA1S)
• Description: A recombinant protein with a N-terminal GST tag corresponding to the amino acid sequence 1743-1838 of Human CACNA1S.
• Sequences: CPRVESSMPEDRKSSTPGSLHEETPHSRSTRENTSRCSAPATALLIQKALVRGGLGTLAADANFIMATGQALGDACQMEPEEVEIMATELLKGREA
• Species: Human
• Molecular Weight: 36.3 kDa
• Source: Wheat Germ
• Introduction: The protein CACNA1S is one of the targets for a number of calcium channel blockers that acts as vasodilators and are used as antihypertensive agents. CACNA1S is a voltage-sensitive calcium channel protein and the immunohistochemical staining with the antibody HPA048892 shows high expression in skeletal muscle where the protein plays an important role in excitation-contraction coupling.
• Purity: >80% by SDS-PAGE and Coomassie blue staining
• Formulation: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.

Pharmaceutical Information

• Applications: CACNA1S is a voltage-sensitive calcium channel protein and the immunohistochemical staining with the antibody HPA048892 shows high expression in skeletal muscle where the protein plays an important role in excitation-contraction coupling.
• Examples of Clinical Use: Be used as antihypertensive agents
• Affected organisms: Humans