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Bone Morphogenetic Protein-13 (BMP-13)

Cat# : THP-0254

Product Datasheets COA :
Catalog# Product Name Availability Size Price Qty
THP-0254 Bone Morphogenetic Protein-13 (BMP-13) July 20, 2024 1 vial $3,998.00
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Cat#:  THP-0254
Product Name:  Bone Morphogenetic Protein-13 (BMP-13)
Description:  This 27.5 kDa protein is obtained by proteolytic processing of a biologically inactive precursor protein of 97.7 kDa. Recombinant Human BMP-13/CDMP-2 is a 27.0 kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains.
Sequences:  TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR
Species:  Human
Molecular Weight:  27.0 kDa
Source:  E. coli
Introduction:  BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains.
Purity:  ≥ 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity:  The ED50 was determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells in the range of 2.0-3.0 µg/ml.
For research use only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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