Anthrax immune globulin human

Specification

• Cat#: THP-0001
• Product Name: Anthrax immune globulin human
• Description: The product is a human immune globulin derived from the plasma of humans immunized with BioThrax (adsorbed anthrax vaccine), which is then further purified.
• Sequences: Not Available
• Species: Human
• Molecular Weight: Not Available
• Cas No: Not Available
• Formula: Not Available
• Endotoxin Level: <0.001 EU per 1 μg of the peptide by the LAL method

Pharmaceutical Information

• Pharmaceutical Application: Anthrax immune globulin human
• Applications: The product is indicated for the treatment of inhalational anthrax in adult and pediatric patients in combination with appropriate antibacterial drugs.
• Examples of Clinical Use: Inhalational anthrax
• Pharmacodynamics: Not Available
• Mechanism of action: Polyclonal anthrax immune globulin is a passive immunizing agent that neutralizes anthrax toxin by binding to Protective Antigen (PA) to prevent PA-mediated cellular entry of anthrax edema factor and lethal factor. It is administered in combination with appropriate antibiotic therapy as the immunoglobulin itself is not known to have direct antibacterial activity against anthrax bacteria, which otherwise may continue to grow and produce anthrax toxins.
• Affected organisms: Not Available
• Targets: Target 1. Protective antigen